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Merck

PLAT

plasminogen activator, tissue

Synonimy:
T-PA, TPA
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(5327) Summary: This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(18791) plasminogen activator, tissue
  • Rat(25692) plasminogen activator, tissue
  • cow(281407) plasminogen activator, tissue
  • sheep(101118332) plasminogen activator, tissue
  • domestic guinea pig(100725281) plasminogen activator, tissue
  • naked mole-rat(101713266) plasminogen activator, tissue
  • Domestic Rabbit(100009556) plasminogen activator, tissue
  • Zebrafish(100320028) plasminogen activator, tissue
  • dog(482840) plasminogen activator, tissue
  • Horse(100050239) plasminogen activator, tissue
  • domestic cat(101100299) plasminogen activator, tissue
  • chicken(426791) plasminogen activator, tissue

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ELISA

Product Number
Opis
Gatunek
Human TPA ELISA, for serum, plasma and cell culture supernatants,
Gatunek
human

Antibodies

Product Number
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-PLAT antibody produced in rabbit, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
Mysie mAb przeciw tkankowemu aktywatorowi plazminogenu (Ab-1) (GMA-043), liquid, clone GMA-043, Calbiochem®,
Reaktywność gatunkowa
human
Zastosowanie
Anti-PLAT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anty-TPA/PLAT, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
ANTI-TPA (CENTER) antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
flow cytometry
immunohistochemistry

western blot

Small Molecule - Inhibitor

Product Number
Opis
Gatunek
Aminocaproic acid, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Kwas aminokapronowy, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
Aminocaproic acid, Pharmaceutical Secondary Standard; Certified Reference Material,
Gatunek
human
Kwas 6-aminoheksanowy, ≥98.5% (NT),
Gatunek
human
6-Aminocaproic acid, ≥99% (titration), powder,
Gatunek
rat, human

Proteins

Product Number
Opis
Gatunek
Tissue plasminogen activator human, ,
Gatunek
human

esiRNA

Product Number
Opis
Gatunek
MISSION® esiRNA, targeting mouse Plat,
Gatunek
mouse
MISSION® esiRNA, targeting human PLAT,
Gatunek
human