MYLK
myosin light chain kinase
Synonimy:
AAT7, KRP, MLCK, MLCK1, MLCK108, MLCK210, MSTP083, MYLK1, smMLCK
Gatunek:
Human MYLK (4638), Mouse Mylk (107589), Rat Mylk (288057), chicken MYLK (396445), dog MYLK (488012), Horse MYLK (100070482), cow MYLK (338037), naked mole-rat Mylk (101704236), Domestic Rabbit MYLK (100009143), domestic guinea pig Mylk (100714177)
Identyfikator UniProtKB:
Identyfikator genu:
- Human(4638) Summary: This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts. [provided by RefSeq, Jul 2008]
- Mouse(107589) myosin, light polypeptide kinase
- Rat(288057) myosin light chain kinase
- chicken(396445) myosin light chain kinase
- dog(488012) myosin light chain kinase
- Horse(100070482) myosin light chain kinase
- cow(338037) myosin light chain kinase
- naked mole-rat(101704236) myosin light chain kinase
- Domestic Rabbit(100009143) myosin light chain kinase
- domestic guinea pig(100714177) myosin light chain kinase
- sheep(443334) myosin light chain kinase
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Antibodies
Product Number
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-Myosin Light Chain Kinase antibody produced in mouse, clone K36, ascites fluid,
Reaktywność gatunkowa
avian, mammals
Zastosowanie
immunoprecipitation (IP)
microarray
western blot
microarray
western blot
Monoclonal Anti-MYLK antibody produced in mouse, clone 1D1, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
western blot
Anti-MYLK antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
proximity ligation assay
western blot
western blot
Anti-MYLK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
Anti-MYLK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
western blot
Small Molecule - Inhibitor
Product Number
Opis
Gatunek
Proteins
Product Number
Opis
Gatunek
Białko MLCK, aktywne, 10 µg, Active, N-terminal 6His-tagged, recombinant, human MLCK, amino acids 1425-1771, for use in Kinase Assays.,
Gatunek
human
MLCK (1425-1776), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Gatunek
human