HDAC8
histone deacetylase 8
Synonimy:
CDLS5, HD8, HDACL1, MRXS6, RPD3, WTS
Gatunek:
Human HDAC8 (55869), Mouse Hdac8 (70315), Rat Hdac8 (363481), Zebrafish hdac8 (406740), cow HDAC8 (540666), domestic cat HDAC8 (101096383), dog HDAC8 (480957), chicken HDAC8 (422182), domestic guinea pig Hdac8 (100721893), naked mole-rat Hdac8 (101697998)
Identyfikator UniProtKB:
Identyfikator genu:
- Human(55869) Summary: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
- Mouse(70315) histone deacetylase 8
- Rat(363481) histone deacetylase 8
- Zebrafish(406740) histone deacetylase 8
- cow(540666) histone deacetylase 8
- domestic cat(101096383) histone deacetylase 8
- dog(480957) histone deacetylase 8
- chicken(422182) histone deacetylase 8
- domestic guinea pig(100721893) histone deacetylase 8
- naked mole-rat(101697998) histone deacetylase 8
- sheep(101110121) histone deacetylase 8
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Antibodies
Product Number
Opis
Reaktywność gatunkowa
Zastosowanie
Przeciwciało anty-HDAC8produkowane u królików, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-HDAC8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-HDAC8 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-HDAC8 antibody produced in mouse, clone 2F4, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
[Zatwierdzone przez KO] Przeciwciało anty-HDAC8, klon 1O2Y5, królicze monoklonalne, ,
Reaktywność gatunkowa
human, rat
Zastosowanie
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Small Molecule - Inhibitor
Proteins
Product Number
Opis
Gatunek
HDAC-8 human, recombinant, expressed in baculovirus infected insect cells, ≥80% (SDS-PAGE),
Gatunek
human