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HDAC5

histone deacetylase 5

Synonimy:
HD5, NY-CO-9
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(10014) Summary: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(15184) histone deacetylase 5
  • Rat(84580) histone deacetylase 5
  • sheep(101113686) histone deacetylase 5
  • domestic guinea pig(100722799) histone deacetylase 5
  • naked mole-rat(101721186) histone deacetylase 5
  • cow(504242) histone deacetylase 5
  • domestic cat(101098019) histone deacetylase 5
  • dog(490941) histone deacetylase 5

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-HDAC5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry
Anti-HDAC5 (Ab-498) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
Anti-phospho-HDAC5 (pSer259) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
western blot
Anti-Phospho-HDAC5-S498 antibody produced in rabbit, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
Anti-Hdac5 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
CI−994, ≥98% (HPLC), powder,
Gatunek
human
Romidepsin, ≥98% (HPLC),
Gatunek
human

Proteins

Numer produktu
Opis
Gatunek
HDAC-5 human, recombinant, expressed in baculovirus infected insect cells, ≥80% (SDS-PAGE),
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Hdac5,
Gatunek
mouse
MISSION® esiRNA, targeting human HDAC5,
Gatunek
human