GRM1
glutamate receptor, metabotropic 1
Synonimy:
GPRC1A, MGLU1, MGLUR1, SCAR13
Gatunek:
Human GRM1 (2911), Mouse Grm1 (14816), Rat Grm1 (24414), domestic guinea pig Grm1 (100730891), naked mole-rat Grm1 (101712477), Domestic Rabbit GRM1 (100356201), Zebrafish grm1 (100150246), dog GRM1 (484024), domestic cat GRM1 (101094104), cow GRM1 (540485) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(2911) Summary: This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
- Mouse(14816) glutamate receptor, metabotropic 1
- Rat(24414) glutamate receptor, metabotropic 1
- domestic guinea pig(100730891) glutamate receptor, metabotropic 1
- naked mole-rat(101712477) glutamate receptor, metabotropic 1
- Domestic Rabbit(100356201) glutamate receptor, metabotropic 1
- Zebrafish(100150246) glutamate receptor, metabotropic 1
- dog(484024) glutamate receptor, metabotropic 1
- domestic cat(101094104) glutamate receptor, metabotropic 1
- cow(540485) glutamate receptor, metabotropic 1
- Horse(100060603) glutamate receptor, metabotropic 1
- chicken(421614) glutamate receptor, metabotropic 1
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Small Molecule - Agonist
Small Molecule - Antagonist
Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Przeciwciało przeciwko metabotropowemu receptorowi glutaminianu 1, Chemicon®, from rabbit,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Przeciwciało anty-mGluR1, Upstate®, from rabbit,
Reaktywność gatunkowa
rat
Zastosowanie
western blot
Monoclonal Anti-Glutamate antibody produced in mouse, clone GLU-4, ascites fluid,
Reaktywność gatunkowa
wide range
Zastosowanie
ELISA
Anti-GRM1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anti-Metabotropic Glutamate Receptor 1α Antibody, pain, CT, Chemicon®, from rabbit,
Reaktywność gatunkowa
human, monkey, rat
Zastosowanie
immunohistochemistry
western blot
western blot
Small Molecule - Inhibitor
Numer produktu
Opis
Gatunek
L-(+)-2-Amino-4-phosphonobutyric acid, optical purity optical purity: ≥95% (HPLC, Marfey′s reagent),
Gatunek
rat, human
Small Molecule - Mixed Agonist/Antagonist
Numer produktu
Opis
Gatunek
L-(+)-2-Amino-4-phosphonobutyric acid, optical purity optical purity: ≥95% (HPLC, Marfey′s reagent),
Gatunek
rat, human
L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Gatunek
rat, human