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Merck

GRIK2

glutamate receptor, ionotropic, kainate 2

Synonimy:
EAA4, GLR6, GLUK6, GLUR6, GluK2, MRT6
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(2898) Summary: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation. [provided by RefSeq, Jul 2008]
  • Mouse(14806) glutamate receptor, ionotropic, kainate 2 (beta 2)
  • Rat(54257) glutamate receptor, ionotropic, kainate 2
  • Zebrafish(556013) glutamate receptor, ionotropic, kainate 2
  • Thale Cress(836176) geminivirus rep interacting kinase 2
  • dog(481938) glutamate receptor, ionotropic, kainate 2
  • cow(615226) glutamate receptor, ionotropic, kainate 2
  • chicken(428628) glutamate receptor, ionotropic, kainate 2
  • domestic guinea pig(100733104) glutamate receptor, ionotropic, kainate 2
  • naked mole-rat(101697577) glutamate receptor, ionotropic, kainate 2
  • sheep(101122701) glutamate receptor, ionotropic, kainate 2

Custom & Knockdown Gene Products

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Small Molecule - Agonist

Product Number
Opis
Gatunek
L-Glutamic acid hydrochloride, ≥99% (HPLC),
Gatunek
human
(±)-AMPA, solid,
Gatunek
rat
(S)-AMPA, ≥97%,
Gatunek
mouse, human, rat
Kainic acid monohydrate, ≥99% (TLC),
Gatunek
human, mouse, rat
(Aminomethyl)phosphonic acid, 99%,
Gatunek
rat, human

Small Molecule - Antagonist

Product Number
Opis
Gatunek
CNQX, ≥98% (HPLC), solid,
Gatunek
rat
NBQX disodium salt hydrate, ≥98% (HPLC),
Gatunek
human
DNQX, ≥98% (TLC),
Gatunek
mouse, rat, human
(±)-AMPA, solid,
Gatunek
rat
(S)-AMPA, ≥97%,
Gatunek
mouse, human, rat

Antibodies

Product Number
Opis
Reaktywność gatunkowa
Zastosowanie
Przeciwciało anty-GRIK2, klon 4B4L9, królicze monoklonalne, ,
Reaktywność gatunkowa
human, rat
Zastosowanie
immunohistochemistry
western blot
Anti-GRIK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
Anti-GRIK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anti-GRIK2 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Zastosowanie
western blot
Anti-GRIK2 (AB2) antibody produced in rabbit, IgG fraction of antiserum,
Reaktywność gatunkowa
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Zastosowanie
immunohistochemistry
western blot

Small Molecule - Mixed Agonist/Antagonist

Product Number
Opis
Gatunek
(±)-AMPA, solid,
Gatunek
rat
Kainic acid monohydrate, ≥99% (TLC),
Gatunek
human, mouse, rat
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Gatunek
rat, human
L-Glutamic acid, BioUltra, ≥99.5% (NT),
Gatunek
rat, human
L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Gatunek
rat, human

esiRNA

Product Number
Opis
Gatunek
MISSION® esiRNA, targeting human GRIK2 (1),
Gatunek
human
MISSION® esiRNA, targeting human GRIK2 (2),
Gatunek
human