GAD2
glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
Synonimy:
GAD65
Gatunek:
Human GAD2 (2572), Mouse Gad2 (14417), Rat Gad2 (24380), Zebrafish gad2 (550403), Thale Cress GAD2 (842908), chicken GAD2 (395395), domestic cat GAD2 (101082244), cow GAD2 (512459), dog GAD2 (487107), sheep GAD2 (101106448) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(2572) Summary: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]
- Mouse(14417) glutamic acid decarboxylase 2
- Rat(24380) glutamate decarboxylase 2
- Zebrafish(550403) glutamate decarboxylase 2
- Thale Cress(842908) glutamate decarboxylase 2
- chicken(395395) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
- domestic cat(101082244) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
- cow(512459) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
- dog(487107) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
- sheep(101106448) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
- naked mole-rat(101698166) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
- domestic guinea pig(100734029) glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
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Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-GAD65 Antibody, clone 3B23 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
affinity binding assay
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
Anti-GAD65 Antibody, from rabbit, purified by affinity chromatography,
Reaktywność gatunkowa
canine, human, mouse, pig, porcine, rat
Zastosowanie
western blot
Anti-Glutamate Decarboxylase Antibody, 65 kDa isoform, clone GAD-6, clone GAD-6, Chemicon®, from mouse,
Reaktywność gatunkowa
human, rat
Zastosowanie
immunohistochemistry
western blot
western blot
Anti-Glutamate Decarboxylase Antibody, 65 kDa isoform, clone GAD-6, clone GAD-6, Chemicon®, from mouse,
Reaktywność gatunkowa
human, rat
Zastosowanie
immunohistochemistry
western blot
western blot
Anti-GAD2/GAD65 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
canine, chimpanzee, human, mouse, rat
Zastosowanie
ELISA
western blot
western blot
Proteins
Numer produktu
Opis
Gatunek