Przejdź do zawartości
Merck

GAB2

GRB2-associated binding protein 2

Synonimy:
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(9846) Summary: This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2009]
  • Mouse(14389) growth factor receptor bound protein 2-associated protein 2
  • Rat(84477) GRB2-associated binding protein 2
  • sheep(101115743) GRB2-associated binding protein 2
  • Domestic Rabbit(100349301) GRB2-associated binding protein 2
  • domestic guinea pig(100732375) GRB2-associated binding protein 2
  • naked mole-rat(101719954) GRB2-associated binding protein 2
  • Zebrafish(564517) GRB2-associated binding protein 2
  • cow(529346) GRB2-associated binding protein 2
  • Horse(100062877) GRB2-associated binding protein 2
  • domestic cat(101101410) GRB2-associated binding protein 2
  • dog(485167) GRB2-associated binding protein 2
  • chicken(419027) GRB2-associated binding protein 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-phospho-GRB2 (pSer159) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry

western blot
Anti-GAB2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
Anti-GAB2 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
western blot
Anti-GAB2 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
western blot
Anti-GAB2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry

esiRNA

Product Number
Opis
Gatunek
MISSION® esiRNA, targeting mouse GAB2,
Gatunek
mouse
MISSION® esiRNA, targeting human GAB2,
Gatunek
human