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Merck

F3

coagulation factor III (thromboplastin, tissue factor)

Synonimy:
CD142, TF, TFA
Gatunek:
Human F3 (2152), Mouse F3 (14066), Rat F3 (25584), chicken F3 (429084), cow F3 (280686), domestic cat F3 (101082330), dog F3 (490153), naked mole-rat F3 (101702267), domestic guinea pig F3 (100135463), sheep F3 (101118918)
Identyfikator UniProtKB:
P13726, D3DT47, Q6FHG2, Q86WH4
Identyfikator genu:
  • Human(2152) Summary: This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
  • Mouse(14066) coagulation factor III
  • Rat(25584) coagulation factor III (thromboplastin, tissue factor)
  • chicken(429084) coagulation factor III (thromboplastin, tissue factor)
  • cow(280686) coagulation factor III
  • domestic cat(101082330) coagulation factor III (thromboplastin, tissue factor)
  • dog(490153) coagulation factor III (thromboplastin, tissue factor)
  • naked mole-rat(101702267) coagulation factor III (thromboplastin, tissue factor)
  • domestic guinea pig(100135463) coagulation factor III
  • sheep(101118918) coagulation factor III (thromboplastin, tissue factor)
  • Domestic Rabbit(100009127) coagulation factor III (thromboplastin, tissue factor)

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ELISA

Numer produktu
Opis
Gatunek
RAB1120
Zestaw ELISA mysiego czynnika krzepnięcia III, for cell culture supernatants, plasma, and serum samples,
Gatunek
mouse
RAB0642
Human F3 / Tissue Factor ELISA Kit, ,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
SAB4702036
Monoklonalny anty-CD142 PE wytwarzany u myszy, ,
Reaktywność gatunkowa
human
Zastosowanie
flow cytometry
SAB4504151
Anti-phospho-Coagulation Factor III (pSer290) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry
western blot
SAB1410355
Anti-F3 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse
Zastosowanie
western blot
MABF3203
Anti-Tissue Factor/CD142 Antibody, clone HTF-1, ,
Reaktywność gatunkowa
bovine, human
Zastosowanie
ELISA
dot blot
flow cytometry
immunohistochemistry
inhibition assay
western blot
ZRB1811
Anti-Tissue Factor Antibody, clone 2L10 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human
Zastosowanie
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot

esiRNA

Numer produktu
Opis
Gatunek
EHU076311
MISSION® esiRNA, targeting human F3,
Gatunek
human