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DRD4

dopamine receptor D4

Synonimy:
D4DR
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(1815) Summary: This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats. [provided by RefSeq, Jul 2008]
  • Mouse(13491) dopamine receptor D4
  • Rat(25432) dopamine receptor D4
  • domestic guinea pig(100733356) dopamine receptor D4
  • naked mole-rat(101708437) dopamine receptor D4
  • chicken(423016) dopamine receptor D4
  • dog(607223) dopamine receptor D4
  • dog(448805) dopamine receptor D4

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Small Molecule - Agonist

Numer produktu
Opis
Gatunek
PD 168,077 maleate salt, powder,
Gatunek
human
Apomorphine hydrochloride hemihydrate, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Ropinirole hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Ropinirole for peak identification 1, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Ropinirole for peak identification 2, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
U-101958 maleate salt, solid,
Gatunek
human
L-745,870 hydrochloride, ,
Gatunek
human
L-741,626, ≥98% (HPLC),
Gatunek
human
Chlorpromazine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Promazine hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-Dopamine D4 Receptor Antibody, extracellular domain, Chemicon®, from rabbit,
Reaktywność gatunkowa
mouse
Zastosowanie
ELISA
western blot
Anti-DRD4 Antibody, clone 2B9, clone 2B9, from mouse,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunocytochemistry
western blot
Anti-Drd4 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
Anti-Dopamine D₄ Receptor Rabbit pAb, lyophilized, Calbiochem®,
Reaktywność gatunkowa
human, rat
Zastosowanie

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
GBR 12909 dihydrochloride, solid, ≥98% (HPLC),
Gatunek
human
Amoxapine, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
Amoxapine, 1.0 mg/mL in methanol, certified reference material, Cerilliant®,
Gatunek
human
Amoxapine, Pharmaceutical Secondary Standard; Certified Reference Material,
Gatunek
human
Amoxapine, ,
Gatunek
human

Small Molecule - Metabolite

Numer produktu
Opis
Gatunek
3-Methoxytyramine hydrochloride, ≥95.5%, crystalline,
Gatunek
human
3-Hydroxy-4-methoxyphenethylamine hydrochloride, ,
Gatunek
human

Small Molecule - Mixed Agonist/Antagonist

Numer produktu
Opis
Gatunek
BP897, >98% (HPLC), solid,
Gatunek
human, rat
Haloperidol, powder,
Gatunek
human, rat
Clozapine, ,
Gatunek
human, rat

Small Molecule - Precursor

Numer produktu
Opis
Gatunek
3,4-Dihydroxy-DL-phenylalanine, ,
Gatunek
mouse, human, rat
3,4-Dihydroxy-L-phenylalanine, ≥98% (TLC),
Gatunek
mouse, human, rat

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Drd4,
Gatunek
mouse