DCC
deleted in colorectal carcinoma
Synonimy:
CRC18, CRCR1, IGDCC1, MRMV1
Gatunek:
Human DCC (1630), Mouse Dcc (13176), Rat Dcc (25311), Zebrafish dcc (569360), dog DCC (483976), cow DCC (537176), Horse DCC (100054013), domestic cat DCC (101098832), domestic guinea pig Dcc (100712666), naked mole-rat Dcc (101705571)
Identyfikator UniProtKB:
Identyfikator genu:
- Human(1630) Summary: This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma. [provided by RefSeq, Oct 2009]
- Mouse(13176) deleted in colorectal carcinoma
- Rat(25311) deleted in colorectal carcinoma
- Zebrafish(569360) deleted in colorectal carcinoma
- dog(483976) deleted in colorectal carcinoma
- cow(537176) deleted in colorectal carcinoma
- Horse(100054013) deleted in colorectal carcinoma
- domestic cat(101098832) deleted in colorectal carcinoma
- domestic guinea pig(100712666) deleted in colorectal carcinoma
- naked mole-rat(101705571) deleted in colorectal carcinoma
- sheep(101118654) deleted in colorectal carcinoma
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Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-DCC antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
dog, guinea pig, horse, human, mouse, rabbit, rat
Zastosowanie
western blot
Anti-DCC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anti-DCC antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunofluorescence
immunofluorescence
Anti-DCC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
Anty-fosfo DCC (Tyr1418), serum, from rabbit,
Reaktywność gatunkowa
rat
Zastosowanie
dot blot
immunofluorescence
western blot
immunofluorescence
western blot
esiRNA
Numer produktu
Opis
Gatunek