Przejdź do zawartości
MilliporeSigma

CYBB

cytochrome b-245, beta polypeptide

Synonimy:
AMCBX2, CGD, GP91-1, GP91-PHOX, GP91PHOX, NOX2, p91-PHOX
Gatunek:
Human CYBB (1536), Mouse Cybb (13058), Rat Cybb (66021), Zebrafish cybb (393386), chicken CYBB (418581), cow CYBB (281112), dog CYBB (491825), sheep CYBB (100036757), Domestic Rabbit CYBB (100008801)
Identyfikator UniProtKB:
P04839, A8K138, Q2PP16
Identyfikator genu:
  • Human(1536) Summary: Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq, Jul 2008]
  • Mouse(13058) cytochrome b-245, beta polypeptide
  • Rat(66021) cytochrome b-245, beta polypeptide
  • Zebrafish(393386) cytochrome b-245, beta polypeptide (chronic granulomatous disease)
  • chicken(418581) cytochrome b-245, beta polypeptide
  • cow(281112) cytochrome b-245, beta polypeptide
  • dog(491825) cytochrome b-245, beta polypeptide (chronic granulomatous disease)
  • sheep(100036757) cytochrome b-245, beta polypeptide
  • Domestic Rabbit(100008801) cytochrome b-245 beta polypeptide

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
AV44276
Anti-CYBB antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rabbit, rat
Zastosowanie
western blot
HPA051227
Anti-CYBB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
SAB4300724
Anty-CYBB, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
western blot
SAB5702937
Przeciwciało anty-NOX2/gp91phox, klon 2Y8W3, królicze monoklonalne, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
western blot
SAB2501192
Anti-CYBB antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
canine, human
Zastosowanie
ELISA
immunohistochemistry
western blot

esiRNA

Numer produktu
Opis
Gatunek
EHU010941
MISSION® esiRNA, targeting human CYBB,
Gatunek
human