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CRH

corticotropin releasing hormone

Synonimy:
CRF
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(1392) Summary: Corticotropin-releasing hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in this protein has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition. [provided by RefSeq, Apr 2010]
  • Mouse(12918) corticotropin releasing hormone
  • Rat(81648) corticotropin releasing hormone
  • chicken(404297) corticotropin releasing hormone
  • dog(486977) corticotropin releasing hormone
  • domestic cat(692345) corticotropin releasing hormone
  • cow(280755) corticotropin releasing hormone
  • sheep(101121525) corticotropin releasing hormone
  • Domestic Rabbit(100301553) corticotropin releasing hormone
  • domestic guinea pig(100719294) corticotropin releasing hormone
  • naked mole-rat(101717831) corticotropin releasing hormone

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Small Molecule - Agonist

Numer produktu
Opis
Gatunek
Astressin, ≥90% (HPLC),
Gatunek
mouse, human, rat

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
Corticotropin Releasing Factor Antagonist, ≥97% (HPLC),
Gatunek
mouse, human, rat

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-CRH antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Anti-CRH antibody produced in chicken, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
western blot
Monoclonal Anti-CRH antibody produced in mouse, clone 2B11, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
Anti-Corticotropin Releasing Factor antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Reaktywność gatunkowa
bovine, canine, frog, human, mouse, pig, rat, sheep
Zastosowanie
immunohistochemistry
microarray

radioimmunoassay

Proteins

Numer produktu
Opis
Gatunek
Corticotropin Releasing Factor Fragment 6-33 human, rat, ≥97% (HPLC),
Gatunek
human
Czynnik uwalniający kortykotropinę, człowiek i szczur, An immunomodulatory neuropeptide that acts to release ACTH from the anterior pituitary and stimulates the sympathetic nervous system and adrenal medulla.,
Gatunek
human
Corticotropin Releasing Factor human, rat, ≥95% (HPLC), powder,
Gatunek
human
Corticotropin Releasing Factor bovine, ≥90% (HPLC), Synthetic,
Gatunek
cow

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Crh,
Gatunek
mouse
MISSION® esiRNA, targeting human CRH,
Gatunek
human