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Merck

CHRM2

cholinergic receptor, muscarinic 2

Synonimy:
HM2
Gatunek:
Human CHRM2 (1129), Mouse Chrm2 (243764), Rat Chrm2 (81645), sheep CHRM2 (101102897), sheep CHRM2 (100628317), Domestic Rabbit CHRM2 (100342878), domestic guinea pig Chrm2 (100715343), naked mole-rat Chrm2 (101714286), chicken CHRM2 (418126), domestic cat CHRM2 (101099790) ...Więcej
Identyfikator UniProtKB:
P08172, Q4VBK6, Q9P1X9
Identyfikator genu:
  • Human(1129) Summary: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(243764) cholinergic receptor, muscarinic 2, cardiac
  • Rat(81645) cholinergic receptor, muscarinic 2
  • sheep(101102897) cholinergic receptor, muscarinic 2
  • sheep(100628317) cholinergic receptor, muscarinic 2
  • Domestic Rabbit(100342878) cholinergic receptor, muscarinic 2
  • domestic guinea pig(100715343) cholinergic receptor, muscarinic 2
  • naked mole-rat(101714286) cholinergic receptor, muscarinic 2
  • chicken(418126) cholinergic receptor, muscarinic 2
  • domestic cat(101099790) cholinergic receptor, muscarinic 2
  • cow(522170) cholinergic receptor, muscarinic 2
  • dog(403858) cholinergic receptor, muscarinic 2

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Small Molecule - Agonist

Numer produktu
Opis
Gatunek
O100
Oxotremorine M, solid,
Gatunek
human
A2251
Acetyl-β-methylcholine chloride, ≥98% (TLC), powder,
Gatunek
human
P6628
Pilocarpine nitrate salt, ≥98% (HPLC),
Gatunek
human
P6503
Pilocarpine hydrochloride, ≥99% (titration), powder,
Gatunek
human
M104
(±)-Muscarine chloride hydrate, ≥98% (HPLC),
Gatunek
human

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
M105
Methoctramine hydrate, ≥97% (NMR), solid,
Gatunek
human
O5015
Oxybutynin chloride, meets EP, USP testing specifications,
Gatunek
human
1164200
Darifenacin hydrobromide, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
SML1102
Darifenacin hydrobromide, ≥98% (HPLC),
Gatunek
human
1485103
Oxybutynin chloride, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
MAB367
Anti-Muscarinic Acetylcholine Receptor m2 Antibody, clone M2-2-B3, clone M2-2-B3, Chemicon®, from rat,
Reaktywność gatunkowa
human, mammals, monkey, rat
Zastosowanie
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
SAB5702535
Przeciwciało anty-muskarynowe AChR M2 (ACM2), klon 3T5W8, królicze monoklonalne, ,
Reaktywność gatunkowa
human, rat
Zastosowanie
immunohistochemistry
western blot
WH0001129M1
Monoclonal Anti-CHRM2 antibody produced in mouse, clone 4B5, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
SAB1405619
Anti-CHRM2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
western blot
AB9452
Przeciwciało przeciwko receptorowi M2 muskarynowego receptora acetylocholiny, Chemicon®, from rabbit,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
A8404
Amitriptyline hydrochloride, ≥98% (TLC), powder,
Gatunek
human
D4526
Doxepin hydrochloride, ~85% E-isomer basis, ≥98% (GC), 15% Z-isomer basis, powder,
Gatunek
human
H1512
Haloperidol, powder,
Gatunek
human, rat
51330
Harmaline, ≥95%,
Gatunek
human, rat

Small Molecule - Ligand

Numer produktu
Opis
Gatunek
A138
Aminobenztropine, solid,
Gatunek
human

Proteins

Numer produktu
Opis
Gatunek
HTS115M
Preparat błonowy ChemiSCREEN Rekombinowany ludzki receptor muskarynowy acetylocholinyM2, Human M2 GPCR membrane prepation for Radioligand binding Assays.,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
EHU120771
MISSION® esiRNA, targeting human CHRM2,
Gatunek
human