CD59
CD59 molecule, complement regulatory protein
Synonimy:
16.3A5, 1F5, EJ16, EJ30, EL32, G344, HRF-20, HRF20, MAC-IP, MACIF, MEM43, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, p18-20
Gatunek:
Human CD59 (966), Rat Cd59 (25407), Zebrafish cd59 (335928), chicken CD59 (423148), cow CD59 (505574), domestic cat CD59 (101092210), dog CD59 (475945), sheep CD59 (101102670), Domestic Rabbit CD59 (100009459), naked mole-rat Cd59 (101726814)
Identyfikator UniProtKB:
Identyfikator genu:
- Human(966) Summary: This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
- Rat(25407) CD59 molecule, complement regulatory protein
- Zebrafish(335928) CD59 molecule, complement regulatory protein
- chicken(423148) CD59 molecule, complement regulatory protein
- cow(505574) CD59 molecule, complement regulatory protein
- domestic cat(101092210) CD59 molecule, complement regulatory protein
- dog(475945) CD59 molecule, complement regulatory protein
- sheep(101102670) CD59 molecule, complement regulatory protein
- Domestic Rabbit(100009459) CD59 molecule, complement regulatory protein
- naked mole-rat(101726814) CD59 molecule, complement regulatory protein
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Numer produktu
Opis
Gatunek
Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Przeciwciało anty-CD59, klon 2/24, clone 2/24, Chemicon®, from mouse,
Reaktywność gatunkowa
human
Zastosowanie
flow cytometry
immunofluorescence
immunofluorescence
Monoclonal Anti-CD59 antibody produced in mouse, clone MEM-43/5, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse
Zastosowanie
flow cytometry
Przeciwciało anty-CD59, klon 2/24, sprzężone z FITC, clone 2/24, Chemicon®, from mouse,
Reaktywność gatunkowa
human
Zastosowanie
flow cytometry
immunofluorescence
immunofluorescence
Monoclonal Anti-CD59-FITC antibody produced in mouse, clone MEM-43, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
flow cytometry
esiRNA
Numer produktu
Opis
Gatunek