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MilliporeSigma

CD59

CD59 molecule, complement regulatory protein

Synonimy:
16.3A5, 1F5, EJ16, EJ30, EL32, G344, HRF-20, HRF20, MAC-IP, MACIF, MEM43, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, p18-20
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(966) Summary: This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Rat(25407) CD59 molecule, complement regulatory protein
  • Zebrafish(335928) CD59 molecule, complement regulatory protein
  • chicken(423148) CD59 molecule, complement regulatory protein
  • cow(505574) CD59 molecule, complement regulatory protein
  • domestic cat(101092210) CD59 molecule, complement regulatory protein
  • dog(475945) CD59 molecule, complement regulatory protein
  • sheep(101102670) CD59 molecule, complement regulatory protein
  • Domestic Rabbit(100009459) CD59 molecule, complement regulatory protein
  • naked mole-rat(101726814) CD59 molecule, complement regulatory protein

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ELISA

Numer produktu
Opis
Gatunek
Human CD59 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Przeciwciało anty-CD59, klon 2/24, clone 2/24, Chemicon®, from mouse,
Reaktywność gatunkowa
human
Zastosowanie
flow cytometry
immunofluorescence
Monoclonal Anti-CD59 antibody produced in mouse, clone MEM-43/5, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse
Zastosowanie
flow cytometry
Przeciwciało anty-CD59, klon 2/24, sprzężone z FITC, clone 2/24, Chemicon®, from mouse,
Reaktywność gatunkowa
human
Zastosowanie
flow cytometry
immunofluorescence
Anty-CD59, ,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
Monoclonal Anti-CD59-FITC antibody produced in mouse, clone MEM-43, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
flow cytometry

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human CD59,
Gatunek
human