ATM
ataxia telangiectasia mutated
Synonimy:
AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1
Gatunek:
Human ATM (472), Mouse Atm (11920), Rat Atm (300711), Zebrafish atm (403064), cow ATM (526824), Horse ATM (100061765), domestic cat ATM (101089291), dog ATM (479450), chicken ATM (395401), Thale Cress ATM (823975) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(472) Summary: The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. [provided by RefSeq, Aug 2010]
- Mouse(11920) ataxia telangiectasia mutated homolog (human)
- Rat(300711) ataxia telangiectasia mutated
- Zebrafish(403064) ataxia telangiectasia mutated
- cow(526824) ataxia telangiectasia mutated
- Horse(100061765) ataxia telangiectasia mutated
- domestic cat(101089291) ataxia telangiectasia mutated
- dog(479450) ataxia telangiectasia mutated
- chicken(395401) ataxia telangiectasia mutated
- Thale Cress(823975) serine/threonine-protein kinase ATM
- naked mole-rat(101718948) ataxia telangiectasia mutated
- domestic guinea pig(100717983) ataxia telangiectasia mutated
- sheep(101105847) ataxia telangiectasia mutated
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Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-ATM antibody produced in mouse, clone 2C10, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunofluorescence
immunofluorescence
Anti-p-ATM (Ser1981) Antibody, clone 1E19, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human
Zastosowanie
affinity binding assay
immunohistochemistry
inhibition assay
western blot
immunohistochemistry
inhibition assay
western blot
Anti-phospho-ATM (Ser1981) Antibody, clone 10H11.E12, Alexa Fluor™ 488, clone 10H11.E12, from mouse, ALEXA FLUOR™ 488,
Reaktywność gatunkowa
human, mouse
Zastosowanie
immunocytochemistry
Anti-Androgen Receptor (C-term) antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP224, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, pig
Zastosowanie
flow cytometry
immunohistochemistry
immunohistochemistry
Anti-ATM Antibody, clone AM9, ascites fluid, clone AM9, Upstate®,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Proteins
Numer produktu
Opis
Gatunek