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Merck

EGFR

epidermal growth factor receptor

Synonimy:
ERBB, ERBB1, HER1, PIG61, mENA
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(1956) Summary: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
  • Mouse(13649) epidermal growth factor receptor
  • Rat(24329) epidermal growth factor receptor
  • fruit fly(37455) Epidermal growth factor receptor
  • cow(407217) epidermal growth factor receptor
  • Horse(100067755) epidermal growth factor receptor
  • domestic cat(100510799) epidermal growth factor receptor
  • dog(404306) epidermal growth factor receptor
  • chicken(396494) epidermal growth factor receptor
  • domestic guinea pig(100725363) epidermal growth factor receptor
  • naked mole-rat(101723771) epidermal growth factor receptor
  • sheep(780479) epidermal growth factor receptor

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ELISA

Numer produktu
Opis
Gatunek
Mouse EGFR ELISA, for serum, plasma and cell culture supernatants,
Gatunek
mouse
Phosphotyrosine EGFR / Epidermal Growth Factor Receptor ELISA Kit, ,
Gatunek
human
Phospho-EGFR (pTyr1068) and pan-EGFR ELISA Kit, for detection of human phospho-egfr (pTyr1068) and pan-egfr in cell and tissue lysates,
Gatunek
human
Cell-Based ELISA for detecting phospho-EGFR (pTyr1068) in cultured cell lines, 96 assays,
Gatunek
human
Cell-Based ELISA for detecting phospho-EGFR (pTyr992) in cultured cell lines, 96 assays,
Gatunek
human

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
Tyrphostin AG 1478, ≥98%,
Gatunek
human, mouse
SU 5416, ≥98% (HPLC),
Gatunek
human, mouse
Genistein, from Glycine max (soybean), ~98% (HPLC),
Gatunek
mouse, human, rat
Genistein, synthetic, ≥98% (HPLC), powder,
Gatunek
mouse, human, rat

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-Phospho-EGFR (Tyr1068) Antibody, clone 3F4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human, monkey
Zastosowanie
affinity binding assay
flow cytometry

immunocytochemistry

immunohistochemistry

western blot
Monoklonalny anty-EGFR, Prestige Antibodies® Powered by Atlas Antibodies, clone CL0822, purified immunoglobulin, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Anti-Phospho-EGFR (y1173) antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM269, purified immunoglobulin,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
Monoklonalneprzeciwciało anty-EGFR(PhosphoTyr1173) produkowane u myszy, clone EM-13,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Anti-EGF Receptor antibody, Rabbit Monoclonal, recombinant, expressed in HEK 293 cells, clone RM294, purified immunoglobulin,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
DAPH, ≥98% (HPLC), solid,
Gatunek
human
Erlotinib hydrochloride, ,
Gatunek
human
Gefitinib for system suitability, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Tyrphostin 1, ≥98%,
Gatunek
human
PKI-166, ≥98% (HPLC),
Gatunek
human

Proteins

Numer produktu
Opis
Gatunek
EGF-receptor human, recombinant, expressed in CHO cells, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture,
Gatunek
human
Epidermal Growth Factor Receptor human, lyophilized powder, ≥15,000 units/mg protein (Bradford),
Gatunek
human
Epidermal Growth Factor Receptor human, buffered aqueous glycerol solution, 5,000-30,000 units/mg protein (Lowry),
Gatunek
human
EGFR Active human, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),
Gatunek
human
EGFR (D746-750 T790M C797S), aktywny, PRECISIO® Kinase, recombinant,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Egfr,
Gatunek
mouse
MISSION® esiRNA, targeting human EGFR,
Gatunek
human