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  • CuCl2-catalyzed one-pot formation of tetrahydroquinolines from N-methyl-N-alkylanilines and vinyl ethers in the presence of t-butylhydroperoxide.

CuCl2-catalyzed one-pot formation of tetrahydroquinolines from N-methyl-N-alkylanilines and vinyl ethers in the presence of t-butylhydroperoxide.

Molecules (Basel, Switzerland) (2007-11-17)
Xianghua Yang, Chanjuan Xi, Yanfeng Jiang
PMID18007402
ABSTRACT

Tetrahydroquinoline skeletons can be formed by a CuCl2-catalyzed one-pot reaction of N-methyl-N-alkylanilines and vinyl ethers in the presence of t-butyl-hydroperoxide.

MATERIALS
Product Number
Brand
Product Description
41700
Sigma-Aldrich
4,N,N-Trimethylaniline, purum, ≥98.0% (GC)
41690
Sigma-Aldrich
4,N,N-Trimethylaniline, catalyst grade (for peroxide polymerization), ≥98.5% (GC)