1441200

Metolazone

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): 7-Chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-6-quinazolinesulfonamide
• Empirical Formula (Hill Notation): C₁₆H₁₆ClN₃O₃S
• CAS Number: 17560-51-9
• Molecular Weight: 365.83
• MDL number: MFCD00069304
• UNSPSC Code: 41116107
• PubChem Substance ID: 329750292
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: metolazone
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: CC1Nc2cc(Cl)c(cc2C(=O)N1c3ccccc3C)S(N)(=O)=O
• InChI: 1S/C16H16ClN3O3S/c1-9-5-3-4-6-14(9)20-10(2)19-13-8-12(17)15(24(18,22)23)7-11(13)16(20)21/h3-8,10,19H,1-2H3,(H2,18,22,23)
• InChI key: AQCHWTWZEMGIFD-UHFFFAOYSA-N
• Gene Information: human ... SLC12A3(6559)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Biochem/physiol Actions

Inhibitor of thiazide-sensitive Na⁺-Cl^- cotransporter; antihypertensive; moderate "loop" diuretic.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable