K2012

Ketoprofen

meets USP testing specifications

• Synonym(s): 2-(3-Benzoylphenyl)propionic acid
• Empirical Formula (Hill Notation): C₁₆H₁₄O₃
• CAS Number: 22071-15-4
• Molecular Weight: 254.28
• EC Number: 244-759-8
• MDL number: MFCD00055790
• UNSPSC Code: 41116107
• PubChem Substance ID: 24896217
• NACRES: NA.21

Properties

• Agency: USP/NF; meets USP testing specifications
• Quality Level: 200
• form: solid
• application(s): pharmaceutical (small molecule)
• SMILES string: CC(C(O)=O)c1cccc(c1)C(=O)c2ccccc2
• InChI: 1S/C16H14O3/c1-11(16(18)19)13-8-5-9-14(10-13)15(17)12-6-3-2-4-7-12/h2-11H,1H3,(H,18,19)
• InChI key: DKYWVDODHFEZIM-UHFFFAOYSA-N
• Gene Information: human ... ALB(213) , IL8RA(3577) , PTGS1(5742) , PTGS2(5743)

Description

Application

• A strong, silk protein-inspired tissue adhesive with an enhanced drug release mechanism for transdermal drug delivery.: Although not exclusively focused on ketoprofen, this study details a novel adhesive for transdermal delivery, highlighting methods that could be adapted for enhancing the delivery of ketoprofen, thus being of interest to biochemists specializing in transdermal drug formulations (Fang et al., 2024).

Biochem/physiol Actions

Non-steroidal anti-inflammatory compound that is selective for COX-1.

Safety Information

• Pictograms: GHS06,GHS09
• Signal Word: Danger
• Hazard Statements: H301,H315,H319,H400
• Precautionary Statements: P264 - P273 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Aquatic Acute 1 - Eye Irrit. 2 - Skin Irrit. 2
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves