PIK3R5
phosphoinositide-3-kinase, regulatory subunit 5
Synonyms:
F730038I15Rik, FOAP-2, P101-PI3K, p101
Species:
Human PIK3R5 (23533), Mouse Pik3r5 (320207), Rat Pik3r5 (497931), cow PIK3R5 (614838), sheep PIK3R5 (101109983), naked mole-rat Pik3r5 (101721762), Domestic Rabbit PIK3R5 (100337757), domestic guinea pig Pik3r5 (100729793), Zebrafish pik3r5 (323588), chicken PIK3R5 (417319) ...More
UniProtKB ID:
Gene ID:
- Human(23533) Summary: Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks are divided into three classes: I, II and III, and only the class I PI3Ks are involved in oncogenesis. This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex, which is a dimeric enzyme, consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55, 87 or 101 kD. This protein recruits the catalytic subunit from the cytosol to the plasma membrane through high-affinity interaction with G-beta-gamma proteins. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found. [provided by RefSeq, Oct 2011]
- Mouse(320207) phosphoinositide-3-kinase, regulatory subunit 5, p101
- Rat(497931) phosphoinositide-3-kinase, regulatory subunit 5
- cow(614838) phosphoinositide-3-kinase, regulatory subunit 5
- sheep(101109983) phosphoinositide-3-kinase, regulatory subunit 5
- naked mole-rat(101721762) phosphoinositide-3-kinase, regulatory subunit 5
- Domestic Rabbit(100337757) phosphoinositide-3-kinase, regulatory subunit 5
- domestic guinea pig(100729793) phosphoinositide-3-kinase, regulatory subunit 5
- Zebrafish(323588) phosphoinositide-3-kinase, regulatory subunit 5
- chicken(417319) phosphoinositide 3-kinase regulatory subunit 5
- Horse(100062810) phosphoinositide-3-kinase, regulatory subunit 5
- domestic cat(101082354) phosphoinositide-3-kinase, regulatory subunit 5
- dog(612805) phosphoinositide-3-kinase, regulatory subunit 5
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PIK3R5 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
proximity ligation assay
western blot
western blot
Anti-PIK3R5 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
immunohistochemistry
immunohistochemistry
Anti-PIK3R5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-PIK3R5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-PIK3R5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
Small Molecule - Inhibitor
Product Number
Description
Species