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Merck

PDX1

pancreatic and duodenal homeobox 1

Synonyms:
GSF, IDX-1, IPF1, IUF1, MODY4, PDX-1, STF-1
Species:
UniProtKB ID:
Gene ID:
  • Human(3651) Summary: The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4). [provided by RefSeq, Jul 2008]
  • Mouse(18609) pancreatic and duodenal homeobox 1
  • Rat(29535) pancreatic and duodenal homeobox 1
  • cow(538927) pancreatic and duodenal homeobox 1
  • sheep(100820739) pancreatic and duodenal homeobox 1
  • naked mole-rat(101715013) pancreatic and duodenal homeobox 1
  • domestic guinea pig(100731776) pancreatic and duodenal homeobox 1
  • Zebrafish(30721) pancreatic and duodenal homeobox 1
  • chicken(771348) pancreatic and duodenal homeobox 1
  • dog(493994) pancreatic and duodenal homeobox 1
  • domestic cat(100240682) pancreatic and duodenal homeobox 1

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ELISA

Product Number
Description
Species
Human PDX-1 ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PDX1 (N-term) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
Anti-PDX1, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, horse, human, mouse, pig, rabbit, rat
Application
western blot
Anti-PDX1 (goat) Antibody, serum, from goat,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
Monoclonal Anti-IPF1 antibody produced in mouse, clone 3F10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Monoclonal Anti-IPF1 antibody produced in mouse, clone 4E12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PDX1,
Species
human
MISSION® esiRNA, targeting mouse Pdx1,
Species
mouse