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Merck

MCL1

myeloid cell leukemia sequence 1 (BCL2-related)

Synonyms:
BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT
Species:
UniProtKB ID:
Gene ID:
  • Human(4170) Summary: This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. [provided by RefSeq, Oct 2010]
  • Mouse(17210) myeloid cell leukemia sequence 1
  • Rat(60430) myeloid cell leukemia sequence 1
  • sheep(554329) myeloid cell leukemia sequence 1 (BCL2-related)
  • domestic guinea pig(100721658) myeloid cell leukemia sequence 1 (BCL2-related)
  • naked mole-rat(101724340) myeloid cell leukemia sequence 1 (BCL2-related)
  • chicken(395674) myeloid cell leukemia sequence 1 (BCL2-related)
  • dog(403537) myeloid cell leukemia sequence 1 (BCL2-related)
  • domestic cat(493970) myeloid cell leukemia sequence 1 (BCL2-related)
  • cow(788087) myeloid cell leukemia sequence 1 (BCL2-related)

Custom & Knockdown Gene Products

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Small Molecule - Antagonist

Product Number
Description
Species
(±)-Gossypol from cotton seeds, ≥95% (HPLC),
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-MCL1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
western blot
Anti-MCL1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-MCL1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Monoclonal Anti-MCL1 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL1128, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-MCL1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Mcl1,
Species
mouse
MISSION® esiRNA, targeting human MCL1,
Species
human