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  • Gli1 identifies osteogenic progenitors for bone formation and fracture repair.

Gli1 identifies osteogenic progenitors for bone formation and fracture repair.

Nature communications (2017-12-13)
Yu Shi, Guangxu He, Wen-Chih Lee, Jennifer A McKenzie, Matthew J Silva, Fanxin Long
ABSTRACT

Bone formation in mammals requires continuous production of osteoblasts throughout life. A common molecular marker for all osteogenic mesenchymal progenitors has not been identified. Here, by lineage-tracing experiments in fetal or postnatal mice, we discover that Gli1

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Anti-Aggrecan Antibody, Chemicon®, from rabbit