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  • Initiation of DNA replication requires actin dynamics and formin activity.

Initiation of DNA replication requires actin dynamics and formin activity.

The EMBO journal (2017-10-07)
Nikolaos Parisis, Liliana Krasinska, Bethany Harker, Serge Urbach, Michel Rossignol, Alain Camasses, James Dewar, Nathalie Morin, Daniel Fisher
PMID28982779
ABSTRACT

Nuclear actin regulates transcriptional programmes in a manner dependent on its levels and polymerisation state. This dynamics is determined by the balance of nucleocytoplasmic shuttling, formin- and redox-dependent filament polymerisation. Here, using