- Upregulation of Epac-1 in Hepatic Stellate Cells by Prostaglandin E
Upregulation of Epac-1 in Hepatic Stellate Cells by Prostaglandin E
The Journal of pharmacology and experimental therapeutics (2017-09-03)
Marlies Schippers, Leonie Beljaars, Eduard Post, Sophie Lotersztajn, Catharina Reker-Smit, Bing Han, Pablo Munoz-Llancao, Martina Schmidt, Klaas Poelstra
PMID28864467
ABSTRACT
Exchange protein activated by cAMP (Epac-1) is an important signaling mechanism for cAMP-mediated effects, yet factors that change Epac-1 levels are unknown. Such factors are relevant because it has been postulated that Epac-1 directly affects fibrogenesis. Prostaglandin E