- Highly enantioselective conjugate addition of nitromethane to chalcones using bifunctional cinchona organocatalysts.
Highly enantioselective conjugate addition of nitromethane to chalcones using bifunctional cinchona organocatalysts.
Organic letters (2005-05-07)
Benedek Vakulya, Szilárd Varga, Antal Csámpai, Tibor Soós
PMID15876031
ABSTRACT
Cinchona alkaloid-derived chiral bifunctional thiourea organocatalysts were synthesized and applied in the Michael addition between nitromethane and chalcones with high ee and chemical yields.