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  • Identification of proximal biomarkers of PKC agonism and evaluation of their role in HIV reactivation.

Identification of proximal biomarkers of PKC agonism and evaluation of their role in HIV reactivation.

Antiviral research (2016-11-28)
Sai Vikram Vemula, Jill W Maxwell, Alexey Nefedov, Bang-Lin Wan, Justin Steve, William Newhard, Rosa I Sanchez, David Tellers, Richard J Barnard, Wade Blair, Daria Hazuda, Andrea L Webber, Bonnie J Howell
PMID27889530
ABSTRACT

The HIV latent CD4 Human CD4 Treatment of primary human CD4 Overall, our results offer new insights into the mechanism of action of PKC agonists, biomarkers of pathway engagement, and the potential role of EGR family in HIV reactivation.