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  • Ph3As-catalyzed wittig-type olefination of aldehydes with diazoacetate in the presence of Na2S2O4.

Ph3As-catalyzed wittig-type olefination of aldehydes with diazoacetate in the presence of Na2S2O4.

The Journal of organic chemistry (2007-07-28)
Peng Cao, Chuan-Ying Li, Yan-Biao Kang, Zuowei Xie, Xiu-Li Sun, Yong Tang
PMID17655362
ABSTRACT

In the presence of sodium hydrosulfite and a catalytic amount of AsPh3 and Fe(TCP)Cl, aldehydes react with ethyl diazoacetate to give the corresponding alpha,beta-unsaturated esters in high yields with excellent stereoselectivities (E/Z > 50/1).