- Synthesis of deuterium-labelled isotopomer of deferasirox.
Synthesis of deuterium-labelled isotopomer of deferasirox.
Journal of labelled compounds & radiopharmaceuticals (2015-02-19)
Freddy H Havaldar, Bhushan Vasant Dabholkar, Ganesh Baban Mule, Suhas Kulkarni
PMID25693166
ABSTRACT
A d4 -labeled isotopomer of deferasirox was synthesized as internal standard for use in a LC/mass spectroscopy (MS)/MS method developed for the simultaneous quantitative determination of deferasirox in human serum. d4 -deferasirox was synthesized from d8 -toluene.
MATERIALS