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Merck

Vasoconstrictor activity of 8-O-acetylharpagide from Ajuga reptans.

Journal of natural products (1992-08-01)
M C Breschi, E Martinotti, S Catalano, G Flamini, I Morelli, A M Pagni
PMID1431938
ABSTRACT

The traditional therapeutic indications for the use of Ajuga reptans (Labiatae) have been investigated. The H2O-soluble part of a crude and partially purified MeOH extract and two isolated iridoids (8-O-acetylharpagide and harpagide), were tested for a biological activity on isolated smooth muscle preparations from guinea pig.