- Scandium triflate catalyzed cycloaddition of imines with 1,1-cyclopropanediesters: efficient and diastereoselective synthesis of multi-substituted pyrrolidines.
Scandium triflate catalyzed cycloaddition of imines with 1,1-cyclopropanediesters: efficient and diastereoselective synthesis of multi-substituted pyrrolidines.
Organic & biomolecular chemistry (2006-01-05)
Yan-Biao Kang, Yong Tang, Xiu-Li Sun
PMID16391772
ABSTRACT
A tandem ring-opening-cyclization reaction of cyclopropanes with imines in the presence of 5 mol% of scandium triflate was developed for the highly diastereoselective synthesis of multi-substituted pyrrolidines.