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  • Difluoro(trimethylsilyl)acetonitrile: synthesis and fluoroalkylation reactions.

Difluoro(trimethylsilyl)acetonitrile: synthesis and fluoroalkylation reactions.

The Journal of organic chemistry (2012-06-20)
Mikhail D Kosobokov, Alexander D Dilman, Vitalij V Levin, Marina I Struchkova
PMID22708637
ABSTRACT

A new silicon reagent, difluoro(trimethylsilyl)acetonitrile, was prepared by insertion of difluorocarbene into silyl cyanide. The obtained silane served as a good cyanodifluoromethylating reagent toward aldehydes, N-tosylimines, N-alkylimines, and enamines under basic or acidic conditions.