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nBu4NI-catalyzed C3-formylation of indoles with N-methylaniline.

Chemical communications (Cambridge, England) (2012-04-20)
Lan-Tao Li, Juan Huang, Hong-Ying Li, Li-Juan Wen, Peng Wang, Bin Wang
ABSTRACT

nBu(4)NI-catalyzed C3-selective formylation of N-H and N-substituted indoles by using N-methylaniline as a formylating reagent was first successfully demonstrated.

MATERIALS
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Sigma-Aldrich
Sodium iodide, ACS reagent, ≥99.5%