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  • Synthesis of indoleamine 2,3-dioxygenase inhibitory analogues of the sponge alkaloid exiguamine A.

Synthesis of indoleamine 2,3-dioxygenase inhibitory analogues of the sponge alkaloid exiguamine A.

Journal of medicinal chemistry (2008-04-09)
Gavin Carr, Marco K W Chung, A Grant Mauk, Raymond J Andersen
PMID18393489
ABSTRACT

Synthetic analogues of the sponge natural product exiguamine A (3) have been prepared and evaluated for their ability to inhibit indoleamine 2,3-dioxygenase in vitro.