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LPLC Media & Accessories

LPLC packed columns with different media for specific chromatography applications.

In low pressure liquid chromatography (LPLC), the mobile phase is forced through the column due to pumps (often peristaltic) operating at low pressures. 

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Inorganic adsorbents

A column is filled with the packing material of choice based on the LPLC application. For a great variety of purification applications, we present a complete line of inorganic adsorbents such as bare silica, bonded silica (C18, C8, aminopropyl, chloropropyl, etc.), Lipid Removal Agent (LRA®), Florisil® magnesium silicate, activated alumina, and Celite® adsorbent. Carbon-based adsorbents like Carboxen™ adsorbents and carbon molecular sieves (CMS) are offered to suit your requirement. Inorganic adsorbents are commonly utilized for purification and isolation of smaller molecular weight compounds.

Resin adsorbents

Resins are most suitable for research-scale separation, purification, and isolation applications. Choose from a vast array of resins from leading manufacturers like DuPont Chemical, Rohm & Haas, Mitsubishi, and Lanxess or consider custom media processing and packaging services of in-stock resins to serve unique application requirements.

Ion Exchange

Ion exchange resin beads are highly ionic, covalently cross-linked, and insoluble polyelectrolytes. These beads are available in two forms, gel resins (microporous resins) with no discrete pores or with a porous structure (macroporous or macroreticular resins). The ion exchange resins can exclude all the ions as their design contains two types of ions: ions that are embedded within the matrix or as free, oppositely charged counter ions. Choose from a comprehensive range of resins including mixed bed ion exchange media, chelating ion exchange media, Amberlite® nuclear ion exchange media, and Sephadex® ion exchange media, among others.

Accessories

The Omnifit® portfolio includes a complete range of accessories like columns, caps, cones, fittings, tubings, variable core connectors, and adaptors. You can also choose from a wide variety of high-quality columns including glass chromatography columns, disposable columns, gravity columns, & accessories, flash columns & components, and ACE columns.

Related Resources

  • Article: Selection Guide for Polymeric Resins
  • Brochure: Resins Selection Guide

    LPLC is a versatile chromatographic technique that has evolved from using open columns and gravity to incorporating pumps and instrumentation. It offers a wide range of media, packed and empty columns, filters, injectors, valves, and tubing. The guide also covers Carboxen® Synthetic carbons, highly engineered derivatized resins with functions in adsorption and hydrophobic interaction chromatography.

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Related Applications
Sample Preparation by Filtration
Filtration separates substances to reduce sample complexity and increase analyte purity, improving analytical results.
Sample Purification
Purification methods for downstream analysis reduce sample complexity, remove interferences, and concentrate analytes for more accurate results.
Solid Phase Extraction (SPE)
Solid phase extraction purifies samples for chromatographic analysis, improving data quality and protecting analytical columns.
Solid Phase Microextraction (SPME)
Solid phase microextraction (SPME) is a solvent-free sample preparation technique that uses coated fibers to extract analytes of interest from a sample before analysis by GC or HPLC.
Large Molecule HPLC
HPLC separates and identifies large biomolecules like proteins and peptides by pumping the sample through a sorbent-packed column.
Liquid Chromatography at Low Pressures
Low pressure liquid chromatography (LPLC) is a chromatographic technique that operates at low pressures to drive the mobile phase onto the column containing a stationary phase by the action of a pump.
Small Molecule HPLC
Small molecules are ions and compounds of molecular weight typically less than 900 daltons. These compounds can be effectively separated and analyzed by HPLC, UHPLC and LC-MS using mainly silica particles or monolithic stationary phases with a broad range of column chemistries (modifications).
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