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SML2874

Sigma-Aldrich

CAY10583

≥98% (HPLC)

Synonym(s):

4′-[[(1-Oxopentyl)phenylamino]methyl][1,1′-biphenyl]-2-carboxylic acid, 4′-{[pentanoyl(phenyl)amino]methyl}-1,1′-biphenyl-2-carboxylic acid, CAY 10583

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About This Item

Empirical Formula (Hill Notation):
C25H25NO3
CAS Number:
862891-27-8
Molecular Weight:
387.47
UNSPSC Code:
51111800
NACRES:
NA.77

Quality Level

100

Assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

InChI

1S/C25H25NO3/c1-2-3-13-24(27)26(21-9-5-4-6-10-21)18-19-14-16-20(17-15-19)22-11-7-8-12-23(22)25(28)29/h4-12,14-17H,2-3,13,18H2,1H3,(H,28,29)

InChI key

IUJTVDNJFPZYBL-UHFFFAOYSA-N

Biochem/physiol Actions

CAY10583 is a potent and selective full agonist for Leukotriene B4 receptor type 2 (BLT2). CAY10583 promotes wound healing and cell proliferation in cultured intestinal epithelial cells.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Lin Luo et al.
Journal of diabetes and its complications, 31(1), 13-20 (2016-10-16)
The synthetic leukotriene B4 receptor type 2 (BLT2) agonist CAY10583 (CAY) accelerates wound healing in diabetic mice by promoting keratinocyte migration. However, its effects on fibroblast activity and granulation are unknown. We investigated the mechanisms by which CAY promotes wound

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