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About This Item
Linear Formula:
H2NC6H4C(O)NHNH2
CAS Number:
Molecular Weight:
151.17
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Assay
95%
form
powder
mp
225-227 °C (lit.)
SMILES string
NNC(=O)c1ccc(N)cc1
InChI
1S/C7H9N3O/c8-6-3-1-5(2-4-6)7(11)10-9/h1-4H,8-9H2,(H,10,11)
InChI key
WPBZMCGPFHZRHJ-UHFFFAOYSA-N
Application
4-Aminobenzoic hydrazide can be used as a reactant to synthesize:
- Acylhydrazone Schiff base ligand by condensation reaction with 2-acetylpyridine.
- Oligomeric transition metal complexes applicable in the fabrication of organic-inorganic hybrid devices with efficient electrical and photoelectrical properties.
- Oxovanadium(IV)-hydrazide complex as a potential radical scavenger.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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A J Kettle et al.
The Biochemical journal, 308 ( Pt 2), 559-563 (1995-06-01)
Myeloperoxidase is the most abundant protein in neutrophils and catalyses the conversion of H2O2 and chloride into HOCl. To help clarify the role of this enzyme in bacterial killing and inflammation, a specific and potent inhibitor needs to be identified.
G O Peelen et al.
Analytical biochemistry, 198(2), 334-341 (1991-11-01)
Analysis of oligosaccharides in complex biological matrices is hampered by the fact that oligosaccharides, closely related in structure, are difficult to separate from each other and that conventional detection procedures (refraction index and uv detection) are not specific enough for
U Burner et al.
The Journal of biological chemistry, 274(14), 9494-9502 (1999-03-27)
Myeloperoxidase is the most abundant protein in neutrophils and catalyzes the production of hypochlorous acid. This potent oxidant plays a central role in microbial killing and inflammatory tissue damage. 4-Aminobenzoic acid hydrazide (ABAH) is a mechanism-based inhibitor of myeloperoxidase that
A J Kettle et al.
The Biochemical journal, 321 ( Pt 2), 503-508 (1997-01-15)
Hypochlorous acid is the most powerful oxidant generated by neutrophils and is likely to contribute to the damage mediated by these inflammatory cells. The haem enzyme myeloperoxidase catalyses its production from hydrogen peroxide and chloride. 4-Aminobenzoic acid hydrazide (ABAH) is
Raphael F Queiroz et al.
Free radical biology & medicine, 53(10), 1942-1953 (2012-09-18)
Tempol (4-hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl) and other cyclic nitroxides have been shown to inhibit the chlorinating activity of myeloperoxidase (MPO) in vitro and in cells. To examine whether nitroxides inhibit MPO activity in vivo we selected acute carrageenan-induced inflammation on the rat paw
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