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MilliporeSigma

TTR

transthyretin

Synonyms:
CTS, CTS1, HsT2651, PALB, TBPA
Species:
Human TTR (7276), Mouse Ttr (22139), Rat Ttr (24856), fruit fly ttr (246932), domestic cat TTR (101085927), dog TTR (480167), chicken TTR (396277), Zebrafish ttr (449556), cow TTR (280948), sheep TTR (443389) ...More
UniProtKB ID:
P02766, Q549C7, Q6IB96, Q9UBZ6, Q9UCM9
Gene ID:
  • Human(7276) Summary: This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc. [provided by RefSeq, Jan 2009]
  • Mouse(22139) transthyretin
  • Rat(24856) transthyretin
  • fruit fly(246932) tetrapter
  • domestic cat(101085927) transthyretin
  • dog(480167) transthyretin
  • chicken(396277) transthyretin
  • Zebrafish(449556) transthyretin (prealbumin, amyloidosis type I)
  • cow(280948) transthyretin
  • sheep(443389) transthyretin
  • domestic guinea pig(100735950) transthyretin
  • naked mole-rat(101726783) transthyretin

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Small Molecule - Antagonist

Product Number
Description
Species
W366706
Diphenyl ether, ≥99%, FG,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
MAB10762
Anti-Transthyretin Antibody, clone 7G8-E11-E7, clone 7G8-E11-E7, from mouse,
Species Reactivity
human
Application
ELISA
western blot
AMAB90649
Monoclonal Anti-TTR antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL0290, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot