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Merck

TP53

tumor protein p53

Synonyms:
BCC7, LFS1, P53, TRP53
Species:
UniProtKB ID:
Gene ID:
  • Human(7157) Summary: This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013]
  • Rat(24842) tumor protein p53
  • Zebrafish(30590) tumor protein p53
  • Horse(100062044) tumor protein p53
  • domestic cat(493847) tumor protein p53
  • dog(403869) tumor protein p53
  • chicken(396200) tumor protein p53
  • cow(281542) tumor protein p53
  • sheep(443421) tumor protein p53
  • domestic guinea pig(100379269) tumor protein p53
  • Domestic Rabbit(100009292) tumor protein p53
  • naked mole-rat(101701769) tumor protein p53

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ELISA

Product Number
Description
Species
Human p53 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human
Rat Tp53 / Cellular Tumor Antigen p53 ELISA Kit, ,
Species
rat

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-acetyl-p53 Antibody (Lys373, Lys382), serum, Upstate®,
Species Reactivity
vertebrates
Application
western blot
Anti-acetyl-p53 (Lys320) Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
bovine, chimpanzee, human
Application
western blot
Anti-p53 Antibody, aa 211-220, clone240, clone PAb240, Chemicon®, from mouse,
Species Reactivity
bovine, chicken, hamster, human, monkey, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-p53 Antibody, clone BP53-12, clone BP53-12, Upstate®, from mouse,
Species Reactivity
human
Application
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-acetyl-p53 (Lys373) Antibody, serum, Upstate®,
Species Reactivity
human
Application
immunoprecipitation (IP)
western blot

Proteins

Product Number
Description
Species
p53-GST (recombinant protein), ,
Species