TNNC1
troponin C type 1 (slow)
Synonyms:
CMD1Z, CMH13, TN-C, TNC, TNNC
Species:
Human TNNC1 (7134), Mouse Tnnc1 (21924), Rat Tnnc1 (290561), chicken TNNC1 (396032), domestic cat TNNC1 (101082986), dog TNNC1 (476595), cow TNNC1 (509486), sheep TNNC1 (101111132), Goat TNNC1 (100860954), domestic guinea pig Tnnc1 (100730526)
UniProtKB ID:
Gene ID:
- Human(7134) Summary: Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z. [provided by RefSeq, Oct 2008]
- Mouse(21924) troponin C, cardiac/slow skeletal
- Rat(290561) troponin C type 1 (slow)
- chicken(396032) troponin C type 1 (slow)
- domestic cat(101082986) troponin C type 1 (slow)
- dog(476595) troponin C type 1 (slow)
- cow(509486) troponin C type 1 (slow)
- sheep(101111132) troponin C type 1 (slow)
- Goat(100860954) troponin C type 1 (slow)
- domestic guinea pig(100730526) troponin C type 1 (slow)
- naked mole-rat(101702386) troponin C type 1 (slow)
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