TLR8
toll-like receptor 8
Synonyms:
CD288
Species:
Human TLR8 (51311), Mouse Tlr8 (170744), Rat Tlr8 (684440), Zebrafish tlr8 (100334317), dog TLR8 (100684828), Horse TLR8 (100054367), domestic cat TLR8 (493658), domestic guinea pig Tlr8 (100713058), naked mole-rat Tlr8 (101726643), Domestic Rabbit TLR8 (100328930) ...More
UniProtKB ID:
Gene ID:
- Human(51311) Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X. [provided by RefSeq, Jul 2008]
- Mouse(170744) toll-like receptor 8
- Rat(684440) toll-like receptor 8
- Zebrafish(100334317) toll-like receptor 8
- dog(100684828) toll-like receptor 8
- Horse(100054367) toll-like receptor 8
- domestic cat(493658) toll-like receptor 8
- domestic guinea pig(100713058) toll-like receptor 8
- naked mole-rat(101726643) toll-like receptor 8
- Domestic Rabbit(100328930) toll-like receptor 8
- cow(532262) toll-like receptor 8
- sheep(554259) toll-like receptor 8
- Goat(100860909) toll-like receptor 8
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