TLR4
toll-like receptor 4
Synonyms:
ARMD10, CD284, TLR-4, TOLL
Species:
Human TLR4 (7099), Mouse Tlr4 (21898), Rat Tlr4 (29260), domestic guinea pig Tlr4 (100724803), naked mole-rat Tlr4 (101715916), Domestic Rabbit TLR4 (100009497), cow TLR4 (281536), Goat TLR4 (100860955), sheep TLR4 (554263), chicken TLR4 (417241) ...More
UniProtKB ID:
Gene ID:
- Human(7099) Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
- Mouse(21898) toll-like receptor 4
- Rat(29260) toll-like receptor 4
- domestic guinea pig(100724803) toll-like receptor 4
- naked mole-rat(101715916) toll-like receptor 4
- Domestic Rabbit(100009497) toll-like receptor 4
- cow(281536) toll-like receptor 4
- Goat(100860955) toll-like receptor 4
- sheep(554263) toll-like receptor 4
- chicken(417241) toll-like receptor 4
- Horse(100066890) toll-like receptor 4
- domestic cat(493698) toll-like receptor 4
- dog(403417) toll-like receptor 4
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ELISA
Product Number
Description
Species
Human TLR-4 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Species
human