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TGM2

transglutaminase 2

Synonyms:
G-ALPHA-h, GNAH, TG2, TGC
Species:
UniProtKB ID:
Gene ID:
  • Human(7052) Summary: Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(21817) transglutaminase 2, C polypeptide
  • Rat(56083) transglutaminase 2, C polypeptide
  • chicken(396432) transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
  • domestic cat(101098215) transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
  • dog(485867) transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
  • naked mole-rat(101699097) transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
  • domestic guinea pig(100379228) transglutaminase 2, C polypeptide
  • cow(281528) transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
  • sheep(101123140) transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)

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ELISA

Product Number
Description
Species
Human Transglutaminase 2 ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Tissue Transglutaminase Antibody, FN binding domain, clone 4G3, clone 4G3, Chemicon®, from mouse,
Species Reactivity
human
Application
immunocytochemistry