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Merck

TCF7L2

transcription factor 7-like 2 (T-cell specific, HMG-box)

Synonyms:
TCF-4, TCF4
Species:
Human TCF7L2 (6934), Mouse Tcf7l2 (21416), Rat Tcf7l2 (679869), Zebrafish tcf7l2 (30510), Horse TCF7L2 (100049930), domestic cat TCF7L2 (101095618), dog TCF7L2 (486894), chicken TCF7L2 (395508), domestic guinea pig Tcf7l2 (100715721), naked mole-rat Tcf7l2 (101710380) ...More
UniProtKB ID:
Q9NQB0, F8W742, F8W7T5, O00185, Q9NQB1, Q9NQB2, Q9NQB3, Q9NQB4
Gene ID:
  • Human(6934) Summary: This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene.[provided by RefSeq, Oct 2010]
  • Mouse(21416) transcription factor 7 like 2, T cell specific, HMG box
  • Rat(679869) transcription factor 7-like 2 (T-cell specific, HMG-box)
  • Zebrafish(30510) transcription factor 7-like 2 (T-cell specific, HMG-box)
  • Horse(100049930) transcription factor 7-like 2 (T-cell specific, HMG-box)
  • domestic cat(101095618) transcription factor 7-like 2 (T-cell specific, HMG-box)
  • dog(486894) transcription factor 7-like 2 (T-cell specific, HMG-box)
  • chicken(395508) transcription factor 7-like 2 (T-cell specific, HMG-box)
  • domestic guinea pig(100715721) transcription factor 7-like 2 (T-cell specific, HMG-box)
  • naked mole-rat(101710380) transcription factor 7-like 2 (T-cell specific, HMG-box)
  • cow(540481) transcription factor 7-like 2 (T-cell specific, HMG-box)
  • sheep(101118068) transcription factor 7-like 2 (T-cell specific, HMG-box)

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Antibodies

Product Number
Description
Species Reactivity
Application
17-10109
ChIPAb+ TCF-4 - ChIP Validated Antibody and Primer Set, from mouse,
Species Reactivity
human, mouse
Application
ChIP
dot blot
immunoprecipitation (IP)
western blot
05-511
Anti-TCF-4 Antibody, clone 6H5-3, clone 6H5-3, Upstate®, from mouse,
Species Reactivity
human, mouse
Application
electrophoretic mobility shift assay
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot