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STK36

serine/threonine kinase 36

Synonyms:
FU
Species:
UniProtKB ID:
Gene ID:
  • Human(27148) Summary: This gene encodes a member of the serine/threonine kinase family of enzymes. This family member is similar to a Drosophila protein that plays a key role in the Hedgehog signaling pathway. This human protein is a positive regulator of the GLI zinc-finger transcription factors. Knockout studies of the homologous mouse gene suggest that defects in this human gene may lead to congenital hydrocephalus, possibly due to a functional defect in motile cilia. Because Hedgehog signaling is frequently activated in certain kinds of gastrointestinal cancers, it has been suggested that this gene is a target for the treatment of these cancers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]
  • Mouse(269209) serine/threonine kinase 36
  • Rat(301516) serine/threonine kinase 36
  • Zebrafish(566154) serine/threonine kinase 36 (fused homolog, Drosophila)
  • chicken(424210) serine/threonine kinase 36, fused homolog (Drosophila)
  • dog(478913) serine/threonine kinase 36
  • domestic cat(101091390) serine/threonine kinase 36
  • cow(508408) serine/threonine kinase 36
  • sheep(101112457) serine/threonine kinase 36
  • naked mole-rat(101701098) serine/threonine kinase 36
  • domestic guinea pig(100725817) serine/threonine kinase 36

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