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Merck

SPI1

spleen focus forming virus (SFFV) proviral integration oncogene

Synonyms:
OF, PU.1, SFPI1, SPI-1, SPI-A
Species:
UniProtKB ID:
Gene ID:
  • Human(6688) Summary: This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(20375) spleen focus forming virus (SFFV) proviral integration oncogene
  • Rat(366126) spleen focus forming virus (SFFV) proviral integration oncogene
  • chicken(395879) spleen focus forming virus (SFFV) proviral integration oncogene spi1
  • domestic cat(101094951) spleen focus forming virus (SFFV) proviral integration oncogene spi1
  • dog(611255) spleen focus forming virus (SFFV) proviral integration oncogene spi1
  • cow(507100) spleen focus forming virus (SFFV) proviral integration oncogene spi1
  • sheep(101119756) spleen focus forming virus (SFFV) proviral integration oncogene spi1
  • naked mole-rat(101707724) spleen focus forming virus (SFFV) proviral integration oncogene spi1
  • domestic guinea pig(100727094) spleen focus forming virus (SFFV) proviral integration oncogene spi1

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