SLC22A12
solute carrier family 22 (organic anion/urate transporter), member 12
Synonyms:
OAT4L, RST, URAT1
Species:
Human SLC22A12 (116085), Mouse Slc22a12 (20521), Rat Slc22a12 (365398), Horse SLC22A12 (100055832), dog SLC22A12 (483761), domestic cat SLC22A12 (101100592), domestic guinea pig Slc22a12 (100721051), naked mole-rat Slc22a12 (101714998), cow SLC22A12 (526067), sheep SLC22A12 (101117630)
UniProtKB ID:
Gene ID:
- Human(116085) Summary: The protein encoded by this gene is a member of the organic anion transporter (OAT) family, and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate, hyperuricemia, is associated with increased incidences of gout, and mutations in this gene cause renal hypouricemia type 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
- Mouse(20521) solute carrier family 22 (organic anion/cation transporter), member 12
- Rat(365398) solute carrier family 22 (organic anion/urate transporter), member 12
- Horse(100055832) solute carrier family 22 (organic anion/urate transporter), member 12
- dog(483761) solute carrier family 22 (organic anion/urate transporter), member 12
- domestic cat(101100592) solute carrier family 22 (organic anion/urate transporter), member 12
- domestic guinea pig(100721051) solute carrier family 22 (organic anion/urate transporter), member 12
- naked mole-rat(101714998) solute carrier family 22 (organic anion/urate transporter), member 12
- cow(526067) solute carrier family 22 (organic anion/urate transporter), member 12
- sheep(101117630) solute carrier family 22 (organic anion/urate transporter), member 12
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