SETDB1
SET domain, bifurcated 1
Synonyms:
ESET, H3-K9-HMTase4, KG1T, KMT1E, TDRD21
Species:
Human SETDB1 (9869), Mouse Setdb1 (84505), Rat Setdb1 (689883), cow SETDB1 (100138100), sheep SETDB1 (101109230), naked mole-rat Setdb1 (101715248), domestic guinea pig Setdb1 (100721293), chicken SETDB1 (395847), dog SETDB1 (483186), domestic cat SETDB1 (101094118)
UniProtKB ID:
Gene ID:
- Human(9869) Summary: This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.[provided by RefSeq, Jun 2011]
- Mouse(84505) SET domain, bifurcated 1
- Rat(689883) SET domain, bifurcated 1
- cow(100138100) SET domain, bifurcated 1
- sheep(101109230) SET domain, bifurcated 1
- naked mole-rat(101715248) SET domain, bifurcated 1
- domestic guinea pig(100721293) SET domain, bifurcated 1
- chicken(395847) SET domain, bifurcated 1
- dog(483186) SET domain, bifurcated 1
- domestic cat(101094118) SET domain, bifurcated 1
- Horse(100059254) SET domain, bifurcated 1
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