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Merck

SEPHS2

selenophosphate synthetase 2

Synonyms:
SPS2, SPS2b
Species:
Human SEPHS2 (22928), Mouse Sephs2 (20768), Rat Sephs2 (308993), Horse SEPHS2 (100063822), domestic cat SEPHS2 (101094068), dog SEPHS2 (489904), domestic guinea pig Sephs2 (100729583), Domestic Rabbit SEPHS2 (100344522), cow SEPHS2 (512060), sheep SEPHS2 (101122245)
UniProtKB ID:
Q99611, Q9BUQ2
Gene ID:
  • Human(22928) Summary: This gene encodes an enzyme that synthesizes selenophosphate from selenide and ATP. Selenophosphate is the selenium donor used to synthesize selenocysteine, which is co-translationally incorporated into selenoproteins at in-frame UGA codons. This protein itself contains a selenocysteine residue in its predicted active site. The 3' UTR of the gene has a stem-loop secondary structure called a selenocysteine insertion sequence (SECIS) element, which allows UGA to direct the incorporation of selenocysteine rather than signal a translational stop. Alternatively spliced transcripts have been identified, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
  • Mouse(20768) selenophosphate synthetase 2
  • Rat(308993) selenophosphate synthetase 2
  • Horse(100063822) selenophosphate synthetase 2
  • domestic cat(101094068) selenophosphate synthetase 2
  • dog(489904) selenophosphate synthetase 2
  • domestic guinea pig(100729583) selenophosphate synthetase 2
  • Domestic Rabbit(100344522) selenophosphate synthetase 2
  • cow(512060) selenophosphate synthetase 2
  • sheep(101122245) selenophosphate synthetase 2

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